Search results for " acyl-benzolar-S-methyl"

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Some Plant Defense Stimulators can induce IL-1β production in human immune cells in vitro

2020

8 pages; International audience; Among Plant Protection Products (PPP), a new emerging category of pesticides act by stimulating plant defense in order to improve plant resistance against microbial pathogens. Given that these compounds, the so-called Plant Defense Stimulators (PDS) act on innate immunity, we tested, using an in vitro approach on human mononuclear leucocytes (PBMC), the potential toxicity (XTT assay) and inflammatory effects (production of IL-1β) of 4 PPP belonging to different chemical families. We found that two products (LBG-01F34® and Regalis®) did not induce any cytotoxicity or IL-1 β production. The product BION-50 WG®, that contains Acibenzolar-S-methyl (ASM) and sili…

[SDV.IMM] Life Sciences [q-bio]/ImmunologyHealth Toxicology and Mutagenesismedicine.medical_treatmentXTT010501 environmental sciencesA vision for the future of pesticide toxicologyToxicology01 natural sciencesPeripheral blood mononuclear cellMicrobiology03 medical and health sciencesLaminarinchemistry.chemical_compound0302 clinical medicineImmune systemlcsh:RA1190-1270medicinePlant defense against herbivoryPesticidesCytotoxicitylcsh:Toxicology. Poisons0105 earth and related environmental sciencesInflammationCell metabolic activityInnate immune systemDanio rerioASM acyl-benzolar-S-methylZebra fishPBMCPlant Defense StimulatorIn vitro3. Good healthPPP Plant Protection productCytokinechemistryPDS Plant Defense StimulatorPBMC peripheral blood mononuclear cellsIL-1β[SDV.IMM]Life Sciences [q-bio]/Immunology030217 neurology & neurosurgeryToxicology Reports

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